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Genetics and animal welfare in the world of the pedigree dog
- P G C Bedford
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- Journal:
- Animal Welfare / Volume 8 / Issue 4 / November 1999
- Published online by Cambridge University Press:
- 11 January 2023, p. 311
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Animal Welfare Special Issue on Genetics and Animal Welfare
- LFM van Zutphen, P G C Bedford
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- Journal:
- Animal Welfare / Volume 8 / Issue 2 / May 1999
- Published online by Cambridge University Press:
- 11 January 2023, p. 96
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The November 1999 issue of Animal Welfare will be published as a Special Issue, devoted to the topical subject of Genetics and Animal Welfare. The journal has established itself as the objective, international forum for quarterly publication of peer-reviewed papers on all aspects of farm, laboratory, zoo, wild and companion animal welfare science - from practical husbandry to ethical debates. In 1998, it ranked in the top 25 per cent of all veterinary/zoological journals covered by the Science Citation Index® - attesting to the quality and impact of its contents.
The origins of carbonatites and related rocks from the Grønnedal-Íka Nepheline Syenite complex, South Greenland: C-O-Sr isotope evidence
- N. J. G. Pearce, M. J. Leng, C. H. Emeleus, C. M. Bedford
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- Mineralogical Magazine / Volume 61 / Issue 407 / August 1997
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- 05 July 2018, pp. 515-529
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The Grønnedal-Íka ring complex (1299 ± 17 Ma) in the Gardar province, South Greenland is composed of a range of layered nepheline syenites which were intruded at a late stage by xenolithic syenite and a plug of carbonatite. The complex was subsequently intruded by a variety of basic dykes, including olivine dolerites, kersantites, vogesites, spessartites, camptonites and an alnöite, and then extensively faulted. The nepheline syenite magmas, produced by fractional crystallisation of basic magmas, show a range in δ13C (−3.86 to −7.57‰) and δ18O (8.27 to 15.12‰), distinctly different to the carbonatites which form a tight group with average δ13C = −4.31 + 0.22 ‰, (1 s.d.) and average δ18O = 7.18 ± 0.41‰ (1 s.d.). Initial 87Sr/86Sr isotope ratios (typically 0.703) suggest the syenites and carbonatites have not assimilated crustal rocks, and therefore the C and O isotope variation within each group is a result of isotopic evolution during fractional crystallisation. A suite of lamprophyre dykes (δ13C −3.86 to −7.86‰ and δ18O 9.12 to 10.81‰) form a coherent group whose stable isotope compositions overlap part of the syenite field, and again are distinctly different from the carbonatites. A single alnöite has δ13C = −3.32‰ and δ18O = 12.34‰ C and O isotope ratios are consistent with origins of syenitic and lamprophyric magmas from a similar source. Despite geochemical evidence which suggests a genetic link between nepheline syenites and carbonatites, C and O isotopic evidence shows that they are not related directly by liquid immiscibility. Comparisons are made between similar rock types from Grønnedal-Íka and from the Gardar Igaliko Dyke Swarm. The possible role of F in controlling δ13C and δ18O during crystallisation of calcite from carbonatite magmas is discussed.
Nutritional geometry of calcium and phosphorus nutrition in broiler chicks. Growth performance, skeletal health and intake arrays
- E. J. Bradbury, S. J. Wilkinson, G. M. Cronin, P. C. Thomson, M. R. Bedford, A. J. Cowieson
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The interaction between calcium (Ca) and non-phytate phosphorus (nPP) in broiler nutrition and skeletal health is highly complex with many factors influencing their digestion, absorption and utilisation. The use of an investigative model such as the geometric framework allows a graphical approach to explore these complex interactions. A total of 600 Ross 308-day-old male broiler chicks were allocated to one of 15 dietary treatments with five replicates and eight birds per replicate. Dietary treatments were formulated to one of three total densities of total Ca+nPP; high (15 g/kg), medium (13.5 g/kg) and low (12 g/kg) and at each density there were five different ratios of Ca : nPP (4, 2.75, 2.1, 1.5 and 1.14 : 1). Weekly performance data was collected and at the end of the experiment birds were individually weighed and the right leg removed for tibia ash analysis. Skeletal health was assessed using the latency to lie (LTL) at day 27. At low Ca and high nPP as well as high Ca and low nPP diets, birds had reduced feed intake, BW gain, poorer feed efficiency and lower tibia ash, resulting in a significant interaction between dietary Ca and nPP (P<0.05). LTL times were negatively influenced by diets having either a broad ratio (high Ca, low nPP) or too narrow a ratio (low Ca, high nPP) indicating that shorter LTL times may be influenced by the ratio of Ca : nPP rather than absolute concentrations of either mineral. The calculated intake arrays show that broilers more closely regulate Ca intake than nPP intake. Broilers are willing to over consume nPP to defend a Ca intake target more so than they are willing to over consume Ca to defend an nPP target. Overall dietary nPP was more influential on performance metrics, however, from the data it may appear that birds prioritise Ca intake over nPP and broadly ate to meet this requirement. As broilers are more willing to eat to a Ca intake target rather than an nPP intake target, this emphasises the importance of formulating diets to a accurately balanced density of Ca : nPP considering the biological importance of both minerals.
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- By Lenard A. Adler, Pinky Agarwal, Rehan Ahmed, Jagga Rao Alluri, Fawaz Al-Mufti, Samuel Alperin, Michael Amoashiy, Michael Andary, David J. Anschel, Padmaja Aradhya, Vandana Aspen, Esther Baldinger, Jee Bang, George D. Baquis, John J. Barry, Jason J. S. Barton, Julius Bazan, Amanda R. Bedford, Marlene Behrmann, Lourdes Bello-Espinosa, Ajay Berdia, Alan R. Berger, Mark Beyer, Don C. Bienfang, Kevin M. Biglan, Thomas M. Boes, Paul W. Brazis, Jonathan L. Brisman, Jeffrey A. Brown, Scott E. Brown, Ryan R. Byrne, Rina Caprarella, Casey A. Chamberlain, Wan-Tsu W. Chang, Grace M. Charles, Jasvinder Chawla, David Clark, Todd J. Cohen, Joe Colombo, Howard Crystal, Vladimir Dadashev, Sarita B. Dave, Jean Robert Desrouleaux, Richard L. Doty, Robert Duarte, Jeffrey S. Durmer, Christyn M. Edmundson, Eric R. Eggenberger, Steven Ender, Noam Epstein, Alberto J. Espay, Alan B. Ettinger, Niloofar (Nelly) Faghani, Amtul Farheen, Edward Firouztale, Rod Foroozan, Anne L. Foundas, David Elliot Friedman, Deborah I. Friedman, Steven J. Frucht, Oded Gerber, Tal Gilboa, Martin Gizzi, Teneille G. Gofton, Louis J. Goodrich, Malcolm H. Gottesman, Varda Gross-Tsur, Deepak Grover, David A. Gudis, John J. Halperin, Maxim D. Hammer, Andrew R. Harrison, L. Anne Hayman, Galen V. Henderson, Steven Herskovitz, Caitlin Hoffman, Laryssa A. Huryn, Andres M. Kanner, Gary P. Kaplan, Bashar Katirji, Kenneth R. Kaufman, Annie Killoran, Nina Kirz, Gad E. Klein, Danielle G. Koby, Christopher P. Kogut, W. Curt LaFrance, Patrick J.M. Lavin, Susan W. Law, James L. Levenson, Richard B. Lipton, Glenn Lopate, Daniel J. Luciano, Reema Maindiratta, Robert M. Mallery, Georgios Manousakis, Alan Mazurek, Luis J. Mejico, Dragana Micic, Ali Mokhtarzadeh, Walter J. Molofsky, Heather E. Moss, Mark L. Moster, Manpreet Multani, Siddhartha Nadkarni, George C. Newman, Rolla Nuoman, Paul A. Nyquist, Gaia Donata Oggioni, Odi Oguh, Denis Ostrovskiy, Kristina Y. Pao, Juwen Park, Anastas F. Pass, Victoria S. Pelak, Jeffrey Peterson, John Pile-Spellman, Misha L. Pless, Gregory M. Pontone, Aparna M. Prabhu, Michael T. Pulley, Philip Ragone, Prajwal Rajappa, Venkat Ramani, Sindhu Ramchandren, Ritesh A. Ramdhani, Ramses Ribot, Heidi D. Riney, Diana Rojas-Soto, Michael Ronthal, Daniel M. Rosenbaum, David B. Rosenfield, Durga Roy, Michael J. Ruckenstein, Max C. Rudansky, Eva Sahay, Friedhelm Sandbrink, Jade S. Schiffman, Angela Scicutella, Maroun T. Semaan, Robert C. Sergott, Aashit K. Shah, David M. Shaw, Amit M. Shelat, Claire A. Sheldon, Anant M. Shenoy, Yelizaveta Sher, Jessica A. Shields, Tanya Simuni, Rajpaul Singh, Eric E. Smouha, David Solomon, Mehri Songhorian, Steven A. Sparr, Egilius L. H. Spierings, Eve G. Spratt, Beth Stein, S.H. Subramony, Rosa Ana Tang, Cara Tannenbaum, Hakan Tekeli, Amanda J. Thompson, Michael J. Thorpy, Matthew J. Thurtell, Pedro J. Torrico, Ira M. Turner, Scott Uretsky, Ruth H. Walker, Deborah M. Weisbrot, Michael A. Williams, Jacques Winter, Randall J. Wright, Jay Elliot Yasen, Shicong Ye, G. Bryan Young, Huiying Yu, Ryan J. Zehnder
- Edited by Alan B. Ettinger, Albert Einstein College of Medicine, New York, Deborah M. Weisbrot, State University of New York, Stony Brook
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- Neurologic Differential Diagnosis
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- 05 June 2014
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- 17 April 2014, pp xi-xx
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- By Rose Teteki Abbey, K. C. Abraham, David Tuesday Adamo, LeRoy H. Aden, Efrain Agosto, Victor Aguilan, Gillian T. W. Ahlgren, Charanjit Kaur AjitSingh, Dorothy B E A Akoto, Giuseppe Alberigo, Daniel E. Albrecht, Ruth Albrecht, Daniel O. Aleshire, Urs Altermatt, Anand Amaladass, Michael Amaladoss, James N. Amanze, Lesley G. Anderson, Thomas C. Anderson, Victor Anderson, Hope S. Antone, María Pilar Aquino, Paula Arai, Victorio Araya Guillén, S. Wesley Ariarajah, Ellen T. Armour, Brett Gregory Armstrong, Atsuhiro Asano, Naim Stifan Ateek, Mahmoud Ayoub, John Alembillah Azumah, Mercedes L. García Bachmann, Irena Backus, J. Wayne Baker, Mieke Bal, Lewis V. Baldwin, William Barbieri, António Barbosa da Silva, David Basinger, Bolaji Olukemi Bateye, Oswald Bayer, Daniel H. Bays, Rosalie Beck, Nancy Elizabeth Bedford, Guy-Thomas Bedouelle, Chorbishop Seely Beggiani, Wolfgang Behringer, Christopher M. Bellitto, Byard Bennett, Harold V. Bennett, Teresa Berger, Miguel A. Bernad, Henley Bernard, Alan E. Bernstein, Jon L. Berquist, Johannes Beutler, Ana María Bidegain, Matthew P. Binkewicz, Jennifer Bird, Joseph Blenkinsopp, Dmytro Bondarenko, Paulo Bonfatti, Riet en Pim Bons-Storm, Jessica A. Boon, Marcus J. Borg, Mark Bosco, Peter C. Bouteneff, François Bovon, William D. Bowman, Paul S. Boyer, David Brakke, Richard E. Brantley, Marcus Braybrooke, Ian Breward, Ênio José da Costa Brito, Jewel Spears Brooker, Johannes Brosseder, Nicholas Canfield Read Brown, Robert F. Brown, Pamela K. Brubaker, Walter Brueggemann, Bishop Colin O. Buchanan, Stanley M. Burgess, Amy Nelson Burnett, J. Patout Burns, David B. Burrell, David Buttrick, James P. Byrd, Lavinia Byrne, Gerado Caetano, Marcos Caldas, Alkiviadis Calivas, William J. Callahan, Salvatore Calomino, Euan K. Cameron, William S. Campbell, Marcelo Ayres Camurça, Daniel F. Caner, Paul E. Capetz, Carlos F. Cardoza-Orlandi, Patrick W. Carey, Barbara Carvill, Hal Cauthron, Subhadra Mitra Channa, Mark D. Chapman, James H. Charlesworth, Kenneth R. Chase, Chen Zemin, Luciano Chianeque, Philip Chia Phin Yin, Francisca H. Chimhanda, Daniel Chiquete, John T. Chirban, Soobin Choi, Robert Choquette, Mita Choudhury, Gerald Christianson, John Chryssavgis, Sejong Chun, Esther Chung-Kim, Charles M. A. Clark, Elizabeth A. Clark, Sathianathan Clarke, Fred Cloud, John B. Cobb, W. Owen Cole, John A Coleman, John J. Collins, Sylvia Collins-Mayo, Paul K. Conkin, Beth A. Conklin, Sean Connolly, Demetrios J. Constantelos, Michael A. Conway, Paula M. Cooey, Austin Cooper, Michael L. Cooper-White, Pamela Cooper-White, L. William Countryman, Sérgio Coutinho, Pamela Couture, Shannon Craigo-Snell, James L. Crenshaw, David Crowner, Humberto Horacio Cucchetti, Lawrence S. Cunningham, Elizabeth Mason Currier, Emmanuel Cutrone, Mary L. Daniel, David D. Daniels, Robert Darden, Rolf Darge, Isaiah Dau, Jeffry C. Davis, Jane Dawson, Valentin Dedji, John W. de Gruchy, Paul DeHart, Wendy J. Deichmann Edwards, Miguel A. De La Torre, George E. Demacopoulos, Thomas de Mayo, Leah DeVun, Beatriz de Vasconcellos Dias, Dennis C. Dickerson, John M. Dillon, Luis Miguel Donatello, Igor Dorfmann-Lazarev, Susanna Drake, Jonathan A. Draper, N. Dreher Martin, Otto Dreydoppel, Angelyn Dries, A. J. Droge, Francis X. D'Sa, Marilyn Dunn, Nicole Wilkinson Duran, Rifaat Ebied, Mark J. Edwards, William H. Edwards, Leonard H. Ehrlich, Nancy L. Eiesland, Martin Elbel, J. Harold Ellens, Stephen Ellingson, Marvin M. Ellison, Robert Ellsberg, Jean Bethke Elshtain, Eldon Jay Epp, Peter C. Erb, Tassilo Erhardt, Maria Erling, Noel Leo Erskine, Gillian R. Evans, Virginia Fabella, Michael A. Fahey, Edward Farley, Margaret A. Farley, Wendy Farley, Robert Fastiggi, Seena Fazel, Duncan S. Ferguson, Helwar Figueroa, Paul Corby Finney, Kyriaki Karidoyanes FitzGerald, Thomas E. FitzGerald, John R. Fitzmier, Marie Therese Flanagan, Sabina Flanagan, Claude Flipo, Ronald B. 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Hackett, Getatchew Haile, Douglas John Hall, Nicholas Hammond, Daphne Hampson, Jehu J. Hanciles, Barry Hankins, Jennifer Haraguchi, Stanley S. Harakas, Anthony John Harding, Conrad L. Harkins, J. William Harmless, Marjory Harper, Amir Harrak, Joel F. Harrington, Mark W. Harris, Susan Ashbrook Harvey, Van A. Harvey, R. Chris Hassel, Jione Havea, Daniel Hawk, Diana L. Hayes, Leslie Hayes, Priscilla Hayner, S. Mark Heim, Simo Heininen, Richard P. Heitzenrater, Eila Helander, David Hempton, Scott H. Hendrix, Jan-Olav Henriksen, Gina Hens-Piazza, Carter Heyward, Nicholas J. Higham, David Hilliard, Norman A. Hjelm, Peter C. Hodgson, Arthur Holder, M. Jan Holton, Dwight N. Hopkins, Ronnie Po-chia Hsia, Po-Ho Huang, James Hudnut-Beumler, Jennifer S. Hughes, Leonard M. Hummel, Mary E. Hunt, Laennec Hurbon, Mark Hutchinson, Susan E. Hylen, Mary Beth Ingham, H. Larry Ingle, Dale T. Irvin, Jon Isaak, Paul John Isaak, Ada María Isasi-Díaz, Hans Raun Iversen, Margaret C. 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Yee, Viktor Yelensky, Yeo Khiok-Khng, Gustav K. K. Yeung, Angela Yiu, Amos Yong, Yong Ting Jin, You Bin, Youhanna Nessim Youssef, Eliana Yunes, Robert Michael Zaller, Valarie H. Ziegler, Barbara Brown Zikmund, Joyce Ann Zimmerman, Aurora Zlotnik, Zhuo Xinping
- Edited by Daniel Patte, Vanderbilt University, Tennessee
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- The Cambridge Dictionary of Christianity
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- 05 August 2012
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- 20 September 2010, pp xi-xliv
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The Influence of Radiant Heat and Air Movement on the Cooling of the Kata-Thermometer
- T. Bedford, C. G. Warner
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- Journal of Hygiene / Volume 33 / Issue 3 / August 1933
- Published online by Cambridge University Press:
- 15 May 2009, pp. 330-348
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The factor of the kata-thermometer as deduced from the relation
F = 0·27θ × cooling time in seconds
is not constant, but increases as θ decreases. The relation between F and θ is shown, and it is recommended that the factor should always be corrected to the value corresponding to a temperature of 60° F.
The rate of heat-loss calculated from the factor determined by the still air method is not the true value, but under-estimates it. If the true value is required it can be obtained with reasonable accuracy by increasing the still air value of the factor by 20 per cent, in the case of the body-temperature kata, and 31 per cent, in the case of the high-temperature instrument. For ordinary use however, it is recommended that the still air factor should continue to be used.
Observations were made in still air with standard kata-thermometers and also with silvered instruments. From these observations, and from determinations of the emissivity of the bulbs, the heat loss by radiation was estimated. The remainder after deducting the radiation loss from the total heat loss gave the loss by convection. Estimations of the convection loss from the silvered and plain katas corresponded closely. An equation is given for the convection loss in still air.
The whirling arm method was used for investigating the effects of air velocities up to 1 m. per sec., corrections being made for swirl. The equation deduced from these observations on the standard body-temperature katas was practically identical with the equation of Hill, Vernon and Hargood-Ash. An equation of similar form was found for the silvered body-temperature kata-thermometers, and equations are also given for the high-temperature instruments. When the true rate of heat-loss is used it is found that one equation can be made to fit the observations with both high-temperature and body-temperature instruments, whether the bulb surfaces are of glass or silver.
It is shown that in places where the temperature of the surrounding surfaces differs from the air temperature, a much more reliable estimate of the air velocity can be obtained if a silvered kata is used instead of the plain glass instrument.
A method is given for measuring the emission of radiation from the surroundings by means of ordinary and silvered kata-thermometers, and it is shown that estimates so made correspond, to within 1 per cent., with the values obtained by direct thermopile measurements.
On Methods of measuring Skin Temperature
- T. Bedford, C. G. Warner
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- Journal:
- Journal of Hygiene / Volume 34 / Issue 1 / February 1934
- Published online by Cambridge University Press:
- 15 May 2009, pp. 81-98
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For the measurement of the temperature of exposed skin surfaces, we have reached the conclusion that the most accurate instrument is a radiation thermopile suitably screened from the effects of wind. As the thermopile does not actually touch the skin it does not interfere with the cutaneous circulation; neither does it hinder the heat-loss from the skin surface. Readings are simply and rapidly made; with the Moll thermopile and the Cambridge unipivot galvanometer used by us a reading can be taken in 4–6 sec. The readings are not influenced by wind if the thermopile is screened, and as the temperatures are measured as differences from that of a blackened surface of known temperature, change of air temperature does not upset the results. The apparatus is easily portable.
By rolling a mercury thermometer over a small area of skin the temperature can be estimated with but very slight error. This method is a reliable one for use where other apparatus is not available; but, it has the disadvantage that each observation takes from 1 to 1½ min. Accurate estimates cannot be obtained by this method in the special cases when the skin temperature is subject to rapid variation.
Under steady conditions accurate estimates can also be made by means of a clinical thermometer protected by a cork wedge, but each observation takes from 4 to 5 min.
Of the types of thermo-junction tested by us the simple Lewis type of junction attached and protected by a strip of surgical tape appears to give the most accurate results. The average error, taking the thermopile values as standard, was only 0·5–0·8° C, and the thermo-junction temperatures were consistently higher than the thermopile values by about this amount.
The Benedict type of junction also gives results which compare reasonably well with those obtained from radiation measurements. In our observations the average error with this type of junction was 0·7–1·3° C, and the error usually had the effect of giving too high a value for the thermo-j unction temperature. Other observers, however, have measured temperatures with this type of junction which appear to be somewhat low, and it appears possible that the temperature of the observer's hand may have influenced the readings obtained.
Forms of apparatus in which the thermo-junction and its leads are exposed to the effects of the air are liable to give very erroneous estimates of skin temperature. In our own comparisons the skin temperature was underestimated by 3–3·5° C. when the Strauss thermo-junction was used; and examples have been drawn from the literature which suggest that, with other apparatus in which the junction was exposed, the temperature was underestimated. If such forms of apparatus are used for measuring skin temperatures beneath the clothing, they may yield fairly reliable results, but in exposed positions considerable errors may arise. This liability to error is particularly serious where there is a wide range of air temperature and of air movement.
Skin temperatures can be measured with considerable accuracy by means of an electrical resistance thermometer.
The Globe Thermometer in Studies of Heating and Ventilation
- T. Bedford, C. G. Warner
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- Journal:
- Journal of Hygiene / Volume 34 / Issue 4 / December 1934
- Published online by Cambridge University Press:
- 15 May 2009, pp. 458-473
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The effects of radiation and convection on the globe thermometer have been studied.
Equations have been obtained, and alignment charts constructed, for the calculation of mean radiation intensity and of equivalent temperature from readings of the globe thermometer, air temperature and air velocity.
The accuracy of these methods has been tested on observations made under industrial conditions. Taking direct thermopile observations as the standard, the mean radiation intensity values calculated from globe thermometer readings had an average error of 1·2 B.Th.U. per sq. ft. per hour. With eupatheoscope readings as standard, equivalent temperature estimates had a mean error of 1·2°.
It is concluded that, while globe thermometer readings alone are unreliable as indications of the effects of the thermal environment, valuable results can be obtained by using the instrument along with an ordinary thermometer and a silvered kata-thermometer.
The Influence of Static Effort on the Respiration and on the Respiratory Exchange
- T. Bedford, H. M. Vernon, C. G. Warner
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- Journal:
- Journal of Hygiene / Volume 33 / Issue 1 / January 1933
- Published online by Cambridge University Press:
- 15 May 2009, pp. 118-150
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(1) The energy cost of static effort.
From previous work it appears that the metabolic cost of maintaining a given tension varies directly as the load, provided no new muscles are brought into play as the result of fatigue or local strain. There is conflict of opinion as to the relation of cost to tension; some workers find a linear relation, while others find a non-linear one.
In the present observations contractions, which were virtually isometric, were made against a powerful spring, while in a standing position.
With constant tension the oxygen cost per contraction varied directly as the duration of the contraction. With constant time and increasing tension the oxygen cost increased more rapidly than the tension.
The duration of contraction varied from ½ to 30 sec., and the tension from 30 to 165 Ib. Over the whole range the oxygen cost per contraction is adequately described by the equation
Q = T1·37 (0·0117 + 0·01090t),
where Q is the oxygen cost per contraction, T is the tension, and t is the duration of contraction.
(2) The effect of static effort on the respiration.
As a measure of hyper-ventilation the ratio of ventilation to oxygen intake is used. It is shown that in dynamic work this ratio falls below the resting value, whereas in static effort of whatever severity the ratio increases considerably above the resting value if the effort is sufficiently prolonged. The rise in the ventilation ratio runs parallel with the feelings of strain which are associated with static effort. Pain causes such a rise in the ratio, and the rise which occurs in static effort is ascribed to the influence of painful sensations of strain.
Observations were made in which the posture alternated between sitting and standing every 40 sec. The change of posture altered the distribution of the strain, and thus the subjective sensations were not so marked as in the experiments with posture unchanged. In consequence of the postural change the ventilation ratio did not rise sensibly above the resting value, and the maximum strength of pull was increased by 6–16 per cent.
Subjective impressions of freshness in relation to environmental conditions
- T. Bedford, C. G. Warner
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- Journal:
- Journal of Hygiene / Volume 39 / Issue 5 / September 1939
- Published online by Cambridge University Press:
- 15 May 2009, pp. 498-511
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A fresh examination has been made of data obtained some years ago when observations were made of the relation between subjective impressions of freshness and the temperature, velocity and humidity of the air. The results are described, and the bearing of certain other factors on freshness impressions is also discussed. The requirements for a pleasant and invigorating atmosphere are stated.
Review of the use of throat packs in nasal surgery
- V Jaiswal, G C Bedford
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- Journal:
- The Journal of Laryngology & Otology / Volume 123 / Issue 7 / July 2009
- Published online by Cambridge University Press:
- 04 February 2009, pp. 701-704
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- July 2009
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Background:
Throat packs are employed in nasal surgery to prevent contamination of the upper aerodigestive tract. Their use is thought to reduce the risk of aspiration and post-operative nausea and vomiting. However, use of throat packs may also be accompanied by increased throat pain. In order to inform our clinical practice, the evidence base for throat pack insertion was reviewed.
Method:A search was made of the Pubmed database from the 1950s to March 2008. Four randomised, controlled, clinical trials were reviewed.
Results:All the trials had significant methodological weakness. In all but one, no power calculations were done. There were inconsistencies in the measurement of pain and heterogeneity of rhinological procedures. The one adequately powered trial could not demonstrate a difference in post-operative nausea and vomiting with the use of throat packs (β error = 20 per cent).
Conclusion:Further, adequately powered trials are required involving patients undergoing rhinological procedures with a higher risk of blood contamination (e.g. functional endoscopic sinus surgery), in order to provide definitive evidence on the morbidity of throat packs in rhinological procedures.
On stratifying 3-jets of functions
- J. O. Bedford, C. G. Gibson
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- Journal:
- Mathematical Proceedings of the Cambridge Philosophical Society / Volume 82 / Issue 3 / November 1977
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- 24 October 2008, pp. 389-400
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- November 1977
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The crucial step in the proof of the Topological Stability Theorem is the construction of a certain contact-invariant Whitney stratification of the sufficient jets in the jet space Jk(n, p). There is therefore a certain intrinsic interest in the construction of natural contact-invariant Whitney stratifications of the jet space. It has long been known that if there are only finitely many contact orbits then these provide a Whitney stratification, but in general there is the double problem of finding a candidate for a Whitney stratification, and then establishing that it has the desired properties. Virtually nothing is known about this problem, so it seems sensible to start by attempting to understand the first non-trivial examples which arise. Since functions are rather better understood than mappings it seems natural to try the case p = 1 first. The complexity of the problem now increases with k. When k = 1, 2 there are only finitely many contact orbits, so we start with k = 3. Having fixed p = 1, k = 3 we turn our attention to n. When n = 1, 2 we still obtain only finitely many contact orbits, as easy computations verify, so we start with n = 3. Thus our first example is J3(3, 1). It is a relatively easy matter to list the contact orbits in this case, and in so doing one is presented with an obvious candidate for a Whitney stratification. Our objective is to show that this candidate is indeed a Whitney stratification.